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THE METHYLATION PATHWAY

It is estimated that One Billion methylation reactions occur in the body each second, maybe worth looking at then?

Methylation is basically the donation of a methyl group or the removal of a methyl group. This process is the ideal mechanism for switching on and off reactions.

 Research shows that approx 45% of the population are low/under methylators, 15% are over methylators and 40% fall within the 'normal' range. Under and over methylators present different symptoms.

Some of the more relevant methylation reactions would be:

  • Turning on/off the expression of genes

  • Turning on/off enzymes

  • Turning on/off detox pathways

  • Required for neurotransmitter production and recycling, Serotonin, Melatonin, Dopamine

  • Required for Homocysteine recycling

An under/low methylator may not be able to 'turn on' certain genes, enzymes, etc while the over methylator may not be able to 'turn off' the expression of the gene, enzyme, etc.

A balanced methylation pathway is crucial for health.